研究業績2009-2011

原著 Original Article 2011

1. Y. Yamada, M. Kitajima, N. Kogure, S. Wongseripipatana, and H. Takayama :
Seven New Monoterpenoid Indole Alkaloids from Gelsemium elegans.
Chem. Asian J.,6(1), 166-173 (2011).

2. K. Foo, T. Newhouse, I. Mori, H. Takayama, and P. S. Baran :
Total Synthesis Guided Structure Elucidation of (+)-Psychotetramine.
Angew. Chem., Int. Ed.,50(12), 2716-2719 (2011).

3. N. Yasobu, M. Kitajima, N. Kogure, Y. Shishido, T. Matsuzaki, M. Nagaoka, and H. Takayama :
Design, Synthesis, and Anti-tumor Activity of 4-Halocolchicines and their Pro-drugs Activated by Cathepsin B.
ACS Med. Chem. Lett.,2(5), 348-352 (2011).

4. M. Lo, K. Matsumoto, M. Iwai, K. Tashima, M. Kitajima, S. Horie, and H. Takayama :
Inhibitory Effect of Iboga-type Indole Alkaloids on Capsaicin-induced Contraction in Isolated Mouse Rectum.
J. Nat. Med., 65 (1), 157-165 (2011).

5. M. Kitajima, M. Iwai, R. Kikura-Hanajiri, Y. Goda, M. Iida, H. Yabushita, and H. Takayama :
Discovery of Indole Alkaloids with Cannabinoid CB1 Receptor Antagonistic Activity.
Bioorg. Med. Chem. Lett.,21(7), 1962-1964 (2011).

6. M. Kitajima, A. Tanaka, N. Kogure, and H. Takayama :
Metacolchicine, A New Colchicinoid from Sandersonia aurantiaca.
Heterocycles,83(8),1903-1907, (2011).

7. K. Katakawa, H. Mito, N. Kogure, M. Kitajima, S. Wongseripipatana, M. Arisawa, and H. Takayama :
Ten New Fawcettimine-related Alkaloids from Three Species of Lycopodium.
Tetrahedron,67(35), 6561-6567 (2011).

8. A. Nakayama, N. Kogure, M. Kitajima, and H. Takayama :
Asymmetric Total Synthesis of a Pentacyclic Lycopodium Alkaloid, Huperzine-Q.
Angew. Chem., Int. Ed.,50(35), 8025-8028 (2011).

9. N. Kogure, N. Katsuta, M. Kitajima, and H. Takayama :
Two New Alkaloids from Crinum asiaticum var. sinicum.
Chem. Pharm. Bull.,59(12), 1545-1548 (2011).

10. M. A. Tan, N. Kogure, M. Kitajima, and H. Takayama :
Total Synthesis of Dubiusamine C, A Plausible Minor Alkaloid in Pandanus dubius.
Phillippine Sci. Lett.,4(2), 98-102 (2011).

11. A. Wibowo, N. Ahmat, A. S. Hamzah, A. S. Sufian, N. H. Ismail, R. Ahmad, F. M. Jaafar, and H. Takayama :
Malaysianol A, a New Trimer Resveratrol Oligomer from the Stem Bark of Dryobalanops aromatica.
Fitoterapia,82(4), 676-681 (2011).

12. M. E. Bungihan, M. A. Tan, M. Kitajima, N. Kogure, S. G. Franzblau, T. E. E. dela Cruz, H. Takayama, and M. G. Nonato :
Bioactive Metabolites of Diaporthe Sp. P133, an Endophytic Fungus Isolated from Pandanus amaryllifolius.
J. Nat. Med.,65(3-4), 606-609 (2011).

原著 Original Article 2010

1. N. Takahashi, T. Ito, Y. Matsuda, N. Kogure, M. Kitajima, and H. Takayama :
Determination of Absolute Configuration of Trimeric Indole Alkaloid, Psychotrimine, by First Asymmetric Total Synthesis.
Chem. Commun.,46(14), 2501-2503 (2010).

2. M. A. Tan, M. Kitajima, N. Kogure, M. G. Nonato, and H. Takayama :
Isolation and Total Syntheses of Two New Alkaloids, Dubiusamines-A and-B, from Pandanus dubius.
Tetrahedron,66(18), 3353-3359 (2010).

3. Y. Wu, M. Kitajima, N. Kogure, Y. Wang, R. Zhang, and H. Takayama :
Two New Aspidosperma Indole Alkaloids from Yunnan Kopsia arborea.
Chem. Pharm. Bull.,58(7), 961-963 (2010).

4. M. A. Tan, M. Kitajima, N. Kogure, M. G. Nonato, and H. Takayama :
New Pyrrolidine Alkaloids from the Roots of Pandanus amaryllifolius.
Tetrahedron Lett.,51(31), 4143-4146 (2010).

5. M. Kitajima, H. Kobayashi, N. Kogure, and H. Takayama :
New Oxindole and Indole Alkaloids from Gelsemium rankinii.
Tetrahedron,66(32), 5987-5992 (2010).

6. M. A. Tan, M. Kitajima, N. Kogure, M. G. Nonato, and H. Takayama :
Isolation of Pandamarilactonine-H from the Roots of Pandanus amaryllifolius and Synthesis of epi-Pandamarilactonine-H.
J. Nat. Prod.,73(8), 1453-1455 (2010).

7. Hasnah M. Sirat, Deny Susanti, Farediah Ahmad, H. Takayama, and M. Kitajima :
Amides, Triterpene and Flavonoids from the Leaves of Melastoma malabathricum L.
J. Nat. Med.,64(4), 492-495 (2010).

原著 Original Article 2009

1. Y. Nishikawa, M. Kitajima, N. Kogure, and H. Takayama :
A Divergent Approach for the Total Syntheses of Cernuane-type and Quinolizidine-type Lycopodium Alkaloids.
Tetrahedron,65(8), 1608-1617 (2009).

2. M. Kitajima, E. Kinoshita, N. Kogure, and H. Takayama :
Two New Alkaloids from Bulbs of Lycoris squamigera
Heterocycles,77(2), 1389-1396 (2009).

3. K. Katakawa, N. Kogure, M. Kitajima, and H. Takayama :
A New Lycopodium Alkaloid, Lycoposerramine-R, with a Novel Skeleton and Three New Fawcettimine-Related Alkaloids from Lycopodium serratum.
Helv. Chim. Acta,92(3), 445-452 (2009).

4. Y. Wu, M. Suehiro, M. Kitajima, T. Matsuzaki, S. Hashimoto, M. Nagaoka, Masato, R. Zhang, and H. Takayama :
Rhazinilam and Quebrachamine Derivatives from Yunnan Kopsia arborea.
J. Nat. Prod.,72(2), 204-209 (2009).

5. N. Kogure, A. Nozoe, M. Kitajima, and H. Takayama :
Nupharic Acid, a New Sesquiterpene Alkaloid from Nuphar japonicum.
Heterocycles,79(1), 1101-1105(2009).

6. Y. Yamada, M. Kitajima, N. Kogure, S. Wongseripipatana, and H. Takayama :
Spectroscopic Analyses and Chemical Transformation for Structure Elucidation of Two Novel Indole Alkaloids from Gelsemium elegans.
Tetrahedron Lett.,50(26), 3341-3344(2009).

7. Y. Wu, M. Kitajima, N. Kogure, Y. Wang, R. Zhang, and H. Takayama :
Kopsiyunnanines F and Isocondylocarpines: New Tubotaiwine-type Alkaloids from Yunnan Kopsia  arborea.
J. Nat. Med.,63(3), 283-289(2009).

8. T. Maruyama, M. Kawamura, R. Kikura-Hanajiri, H. Takayama, and Y. Goda :
The Botanical Origin of Kratom (Mitragyna speciosa; Rubiaceae) Available s Abused Drugs in the Japanese Markets.
J. Nat. Med.,63(3), 340-344(2009).

9. T. Ito, M. Kitajima, and H. Takayama :
Asymmetric Total Synthesis of Reported Structure of Eudistomidin B, an Indole Alkaloid Isolated from a Marine Tunicate.
Tetrahedron Lett.,50(31), 4506-4508(2009).

10. R. Nakabayashi, M. Kusano, M. Kobayashi, T. Tohge, K. Yonekura-Sakakibara, N. Kogure, M. Yamazaki, M. Kitajima, K. Saito, H. Takayama :
Metabolomics-oriented Isolation and Structure Elucidation of 37 Compounds Including Two Anthocyanins from Arabidopsis thaliana.
Phytochemistry,70(8), 1017-1029(2009).

11. R. Kikura-Hanajiri, M. Kawamura, T. Maruyama, M. Kitajima, H. Takayama, Y. Goda :
Simultaneous Analysis of Mitragynine, 7-Hydroxymitragynine, and Other Alkaloids in the Psychotropic Plant "Kratom" (Mitragyna speciosa) by LC-ESI-MS.
Forensic Toxicology,27(2), 67-74(2009).

12. T. Tanaka, N. Kogure, M. Kitajima, and H. Takayama :
Asymmetric Total Syntheses of Cyclic-Nitrone-Containing Phlegmarine-Type Lycopodium Alkaloids, Lycoposerramines-X and –Z.
J. Org. Chem.,74(22), 8675-8680(2009).

13. A. Nakayama, N. Kogure, M. Kitajima, and H. Takayama :
First Asymmetric Total Syntheses of Fawcettimine-Type Lycopodium Alkaloids, Lycoposerramine-C and Phlegmariurine-A.
Org. Lett.,11(23), 5554-5557(2009).

14. I. Musthapa, J. Latip, H. Takayama, L. D.Juliawaty, E. H. Hakim, Y. M. Syah :
Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells.
Nat. Prod. Commun.,4(7), 927-930(2009).