2020-2016
2020
105.
Shingo Harada, Mayu Kobayashi, Masato Kono, and Tetsuhiro Nemoto:
Site-Selective and Chemoselective C–H Functionalization for the Synthesis of Spiroaminals via a Silver-Catalyzed Nitrene Transfer Reaction
ACS Catal., 10, 13296 (2020).
104.
Haruka Homma, Shingo Harada, Tsubasa Ito, Ayaka Kanda, and Tetsuhiro Nemoto:
Atypical Dearomative Spirocyclization of β–Naphthols with Diazoacetamides Using a Silver Catalyst
Org. Lett., 22, 8132 (2020).
103.
Shingo Harada, Mai Yanagawa, and Tetsuhiro Nemoto:
Dual-Functional Enone-Directing Group/Electrophile for Sequential C-C Bond Formation with α-Diazomalonates: A Short Synthesis of Chiral 3,4-Fused Tricyclic Indoles
ACS Catal., 10, 11971 (2020).
102.
Mai Yanagawa, Mayu Kobayashi, Mitsuru Ikeda, Shingo Harada, and Tetsuhiro Nemoto:
Computational Study on the Synergic Effect of Brønsted Acid and Hydrogen–Bonding Catalysis for the Dearomatization Reaction go Phenols with Diazo Functionality
Chem. Pharm. Bull., 68, 1104 (2020).
101.
Koki Matsumoto, Masaya Nakajima, and Tetsuhiro Nemoto:
Visible Light-Induced Direct S0→Tn Transition of Benzophenone Promotes C(sp3)-H Alkynylation of Ethers and Amides
J. Org. Chem., 85, 11802 (2020).
100.
Jun Ueda, Shingo Harada, Ayaka Kanda, Hiroki Nakayama, and Tetsuhiro Nemoto:
Silver-Catalyzed, Chemo- and Enantioselective Intermolecular Dearomatization of Indoles to Access Sterically Congested Azaspiro Frameworks
J. Org. Chem., 85, 10934 (2020).
99.
Takahito Kuribara, Koki Matsumoto, Sho Nagasawa, Yuta Suzuki, Masaya Nakajima, Yasumasa Hamada, and Tetsuhiro Nemoto:
Computational studies of the mechanism of Pd-Catalyzed Intramolecular Friedel-Crafts allylic alkylation of phenols
Tetrahedron, 76, 131146 (2020).
98.
Takahito Kuribara, Masaya Nakajima, and Tetsuhiro Nemoto:
Visible-Light-Induced Metal-/Photocatalyst-Free C–H Bond Imidation of Arenes
Org. Lett., 22, 2235 (2020).
97.
Masaya Nakajima, Yusuke Kondo, Shun-ichi Nakano, Yusuke Adachi, Dongil Choi, Robert Franzen, and Tetsuhiro Nemoto:
Radical cascade cyclization for synthesizing 3,4-fused tricyclic benzofuran derivatives
Tetrahedron Lett., 61, 151754 (2020).
96.
Masaya Nakajima, Sho Nagasawa, Koki Matsumoto, Takahito Kuribara, Atsuya Muranaka, Masanobu Uchiyama, and Tetsuhiro Nemoto:
Direct S0→Tn Transition in the Photoreaction of Heavy‐Atom‐Containing Molecules
Angew. Chem. Int. Ed., 59, 6847 (2020).
2019
95.
Shingo Harada, Koki Tanikawa, Haruka Homma, Chigaya Sakai, Tsubasa Ito, and Tetsuhiro Nemoto:
Silver‐Catalyzed Asymmetric Insertion into Phenolic O−H Bonds using Aryl Diazoacetates and Theoretical Mechanistic Studies
Chem. Eur. J., 25, 12058 (2019).
[Hot Paper]
94.
Shingo Harada, Chigaya Sakai, Koki Tanikawa, and Tetsuhiro Nemoto:
Gold-catalyzed chemoselective formal (3+2)-Annulation reaction between β-naphthols and methyl aryldiazoacetate
Tetrahedoron, 75, 3650 (2019).
93.
Masato Kono, Shingo Harada, Tomoyuki Nozaki, Yoshinori Hashimoto, Shun-ichi Murata, Harald Gröger, Yusuke Kuroda, Ken-ichi Yamada, Kiyosei Takasu, Yasumasa Hamada, and Tetsuhiro Nemoto:
Asymmetric Formal Synthesis of (+)-Catharanthine via Desymmetrization of Isoquinuclidine
Org. Lett., 21, 3750 (2019).
92.
Koki Matsumoto, Masaya Nakajima, and Tetsuhiro Nemoto:
Determination of the Best Functional and Basis Sets for Optimization of the Structure of Hypervalent Iodines and Calculation of their First and Second Bond Dissociation Enthalpies
J. Phys. Org. Chem., e3961, 1 (2019).
91.
Tomoaki Fukuda, Takeaki Hara, Shinji Ina, Tetsuhiro Nemoto, and Takeshi Oshima:
Development of a Synthetic Process for K-8986, an H1-Receptor Antagonist
Org. Process Res. Dev., 23, 470 (2019).
90.
Rui Qin, Shihori Takayanagi, Yusuke Kondo, Jiawei Li, Naoki Shiga, Masaya Nakajima, Ken-ichi Shinohara, Natsumi Yoda, Takayoshi Suzuki, Atsushi Kaneda, and Tetsuhiro Nemoto:
Synthsis of LSD1 Inhibitor-Pyrrole-Imidazole Polyamide Conjugates for Region-Specific Alterations of Histone Modification
Heterocycles., 99, 891 (2019).
89.
Tetsuhiro Nemoto:
Synthesis of 3,4-Fused Tricyclic Indoles Using a 3-Alkylidene Indolines as a Precursor
Chem. Rec., 19, 320 (2019).
88.
Masato Kono, Shingo Harada, Tetsuhiro Nemoto:
Exploring New Reactivity of Metal Carbenoids and its Application to Organic Synthesis
J. Synth. Org. Chem. Jpn., 77, 49 (2019).
87.
Masato Kono, Shingo Harada, Tetsuhiro Nemoto:
Chemoselective Intramolecular Formal Insertion Reaction of Rh-Nitrenes into an Amide Bond Over C-H Insertion
[Hot Paper]
Chem. Eur. J., 25, 3119 (2019).
2018
86.
Yoshinori Hashimoto, Masato Kono, Shingo Harada, Tetsuhiro Nemoto:
Urea Insertion Reaction of Rhodium-Carbenoid
[Highlighted Paper selected by Editor-in-Chief]
[Cover Figure]
[Featured Article]
Chem. Pharm. Bull., 66, 1041 (2018).
85.
Tetsuhiro Nemoto, Shingo Harada, and Masaya Nakajima:
Synthetic Methods for 3,4-Fused Tricyclic Indoles via Indole Ring Formation
Asian J. Org. Chem., 7, 1730 (2018).
84.
Kai Zhang, Hidetoh Toki, Yuko Fujita, Min Ma, Lijia Chang, Youge Qu, Shingo Harada, Tetsuhiro Nemoto, Akiko Mizuno-Yasuhira, Jun-ichi Yamaguchi, Shigeyuki Chaki, and Kenji Hashimoto:
Lack of Deuterium Isotope Effects in the Antidepressant Effects of (R)-Ketamine in a Chronic Social Defeat Stress Model
Psychopharmacology, 235, 3177 (2018).
83.
Kokiladevi Alagarswamy, Ken-ichi Shinohara, Shihori Takayanagi, Masaki Fukuyo, Atsushi Okabe, Bahityar Rahmutulla, Natsumi Yoda, Rui Qin, Naoki Shiga, Masahiro Sugiura, Hiroaki Sato, Kazuko Kita, Takayoshi Suzuki, Tetsuhiro Nemoto, and Atsushi Kaneda:
Region-Specific Alteration of Histon Modification by LSD1 Inhibitor Conjugated with Pyrrole-Imidazole Polyamide
Oncotarget, 9, 29316 (2018).
82.
Jun Ueda, Shingo Harada, Hiroki Nakayama, Tetsuhiro Nemoto:
Silver-Catalyzed Regioselective Hydroamination of Alkenyl Diazoacetates to Synthesize γ-Amino Acid Equivalents
Org. Biomol. Chem., 16, 4675 (2018).
[A High-Profile Web Themed Issue on "Carbenes in Organic Synthesis"]
81.
Kazuki Tsuruda, Takahisa Tokumoto, Naoya Inoue, Masaya Nakajima, and Tetsuhiro Nemoto:
Synthesis of 7-Membered Ring Carbocycles via a Palladium-Catalyzed Intramolecular Allylic Alkylation-Isomerization-Cope Rearrangement Cascade
Eur. J. Org. Chem., 22, 2836 (2018).
80.
Hiroki Nakayama, Shingo Harada, Ayaka Kanda, Irene Mei-Yi Kwok, Tetsuhiro Nemoto:
Binary additive effect of benzoic acid in ipso-Friedel-Crafts-type dearomatization of phenols using a chiral silver phosphate
Tetrahedron, 74, 2435 (2018).
79.
Shingo Harada, Ryota Kajihara, Risa Muramoto, Promsuk Jutabhab, Naohiko Anzai, Tetsuhiro Nemoto:
Catalytic Asymmetric Synthesis of α-Methyl-p-Boronophenylalanine
Bioorg. Med. Chem. Lett., 28, 1915 (2018).
78.
Ryota Kajihara, Shingo Harada, Jun Ueda, Tetsuhiro Nemoto:
Synthesis of functionalized iodoalkenes using a multicomponent reaction triggered by electrophilic iodination of alkenyldiazoacetates
Tetrahedron Lett., 59, 1906 (2018).
77.
Takahito Kuribara, Jun Ueda, Yuito Tanaka, Masaya Nakajima, Shingo Harada, and Tetsuhiro Nemoto:
Intramolecular Heck Insertion of A Diene-Allylic Amination Cascade to Synthesize A 2-Alkenyl-3,4-fused Indole Structure
Heterocycles, 97, 1175 (2018).
76.
Dongil Choi, Naoki Shiga, Robert Franzen, Tetsuhiro Nemoto:
Acid‐Promoted Cascade Cyclization to Produce 2‐(4′‐Alkoxyaryl)‐3,4‐Fused Tricyclic Dihydrobenzopyrans via a Vinylidene para‐Quinone Methide Intermediate
Eur. J. Org. Chem., 15, 1785 (2018).
75.
Shun-ichi Nakano, Yasumasa Hamada, Tetsuhiro Nemoto:
Enantioselective formal synthesis of (-)-aurantioclavine using Pd-catalyzed cascade cyclization and organocatalytic asymmetric aziridination
Tetrahedron Lett., 59, 760 (2018).
74.
Shingo Harada, Irene Mei-Yi Kwok, Hiroki Nakayama, Ayaka Kanda, Tetsuhiro Nemoto:
Merging Brensted Acid and Hydrogen‐Bonding Catalysis: Metal‐Free Dearomatization of Phenols via ipso‐Friedel‐Crafts Alkylation to Produce Functionalized Spirolactams
Adv. Synth. Catal., 360, 801 (2018).
2017
73.
Hiroki Nakayama, Shingo Harada, Masato Kono, Tetsuhiro Nemoto:
Chemoselective Asymmetric Intramolecular Dearomatization of Phenols with α-Diazoacetamides Catalyzed by Silver Phosphate
J. Am. Chem. Soc., 139, 10188 (2017).
Highlighted in Chem-Station(スポットライトリサーチ).
プレスリリース(千葉大学)
72.
Masato Kono, Shingo Harada, Tetsuhiro Nemoto:
Rhodium-Catalyzed Stereospecific C−H Amination for the Construction of Spiroaminal Cores:
Reactivity Difference between Nitrenoid and Carbenoid Species against Amide Functionality
Chem. Eur. J., 23, 7428-7432 (2017).
71.
Naoki Shiga, Shihori Takayanagi, Risa Muramoto, Tasuku Murakami, Rui Qin, Yuta Suzuki, Ken-ichi Shinohara, Astushi Kaneda, and Tetsuhiro Nemoto:
Synthesis of Pyrrole-Imidazole Polyamide Oligomers Based on a Copper-catalyzed Cross-Coupling
Bioorg. Med. Chem. Lett., 27, 2197-2200 (2017).
70.
Yuito Tanaka, Yuta Suzuki, Yasumasa Hamada, and Tetsuhiro Nemoto:
Total Synthesis of Fargesine Using a Platinum-Catalyzed Intramolecular Friedel-Crafts-Type C-H Coupling-Allylic Amination Cascade
Heterocycles, 95, 243-350 (2017).
69.
Naoya Inoue, Shun-ichi Nakano, Shingo Harada, Yasumasa Hamada, Tetsuhiro Nemoto:
Synthetic Study of Dragmacidin E: Construction of the Core Structure Using Pd-Catalyzed Cascade Cyclization and Rh-Catalyzed Aminoacetoxylation
J. Org. Chem. 82, 2787-2793 (2017).
2016
68.
Ken-ichi Shinohara, Nastumi Yoda, Kiyoko Takane, Takayoshi Watanabe, Masaki Fukuyo, Kyoko Fujiwara, Kzuko Kita, Hiroki Nagase, Tetsuhiro Nemoto, and Atsushi Kaneda:
Inhibition of DNA Methylation at the MKH1 Promoter Region Using Pyrrole-Imidazole Polyamide
ACS Omega 1, 1164-1172 (2016).
67.
Shingo Harada, Ryosuke Kato, and Tetsuhiro Nemoto:
Construction of functionalized azapolycyclic architectures via formal amide insertion at a low catalyst loading of copper trifluoroacetylacetonate
Adv. Synth. Catal.,358, 3123-3129, (2016).
66.
Tetsuhiro Nemoto, and Yasumasa Hamada:
Synthesis of Spirocyclic and Fused-Cyclic Compounds Using Transition Metal-Catalyzed Intramolecular Friedel-Crafts-Type Reactions of Phenol Derivatives
Synlett,27, 2301-2313, (2016).
65.
Mami Yamaguchi, Minami Hayashi, Yasumasa Hamada, and Tetsuhiro Nemto:
Synthetic Study of Pactamycin: Enantioselective Construction of the Pactamycin Core with Five Contiguous Stereocenters
Org. Lett.,18, 2347-2350, (2016).
64.
Tetsuhiro Nemoto, Risa Muramoto, Tanachote Ruengsatra, and Yasumasa Hamada:
Formal Enantioselective Synthesis of (-)-Allosamizoline Using Chiral Diamine-Catalyzed Asymmeric Aziridination of Cyclic Enones
Tetrahedron,72, 1991-1997, (2016).
63.
Yuta Suzuki, Yuito Tanaka, Shun-ichi Nakano, Kosuke Dodo, Natsumi Yoda, Ken-ichi Shinohara, Kazuko Kita, Atsushi Kaneda, Mikiko Sodeoka, Yasumasa Hamada, and Tetsuhiro Nemoto:
Platinum-Catalyzed Friedel-Crafts-Type C-H coupling-Allylic Amination Cascade to Synthesize 3,4-Fused Tricyclic Indoles
Chem. Eur. J.,22, 4418-4421, (2016).
62.
Masato Kono, Shingo Harada, Yasumasa Hamada, and Tetsuhiro Nemoto:
Formal amide insertion strategy for the synthesis of anatoxin-a using rhodium catalysis
Tetrahedron,72, 1395-1399, (2016).
