Arai, S.; Inagaki, S.; Nakajima, M.; Nishida, A.

“Regio-divergent Nickel Catalysis: Intramolecular [4+2] and [2+2] Cycloaddition Reactions Between Vinylallenes and Alkynes”

Chem. Commun. 2021, 57, 11268-11271.

Kawata, Y.; Arai, S.; Nakajima, M.; Nishida, A.

“Regio- and stereoselective synthesis of cyclobutanes by nickel-catalyzed homodimerizative [2 + 2] cycloaddition using allenamides.”

Tetrahedron Lett. 2021, 69, 152974.

Shigeru Arai, Atsushi Nishida

“Synthesis of Nitrogen Heterocycles through Cyanative Cyclization and Cycloaddition Reactions under Transition Metal Catalysis”
Heterocycles 2020, 100, 1949-1978.

Arai, S.; Sato, Y.; Ito, N.; Nishida, A.

“Cobalt-catalyzed hydrocyanation and hydroarylation of enamines.”

Tetrahedron Lett. 2019, 60, 151314-151317.

Arai, S.; Kawata, Y.; Amako, Y.; Nishida, A.

“Nickel-catalyzed [2+2] cycloaddition reaction using bisallenes.”

Tetrahedron Lett. 2019, 60, 151168-151171.

Arai, S.; Izaki, A.; Amako, Y.; Nakajima, M.; Uchiyama, M.; Nishida, A.

“Regioselective [2+2+2] cycloaddition reaction using allene-ynes with simple allenes under nickel catalysis.”

Adv. Syn. Catal. 2019, 361, 4882-4887.

Selected as Very Important Publication (VIP) and front cover picture.

Hori, H.; Arai, S.; Nishida, A.

“Cobalt-catalyzed cyclization with the introduction of cyano, acyl and aminoalkyl groups.”

Org. Biomol. Chem. 2019, 17, 4783-4788.

荒井秀、天児由佳、堀弘人、西田篤司

“ニッケル触媒を用いる炭素―炭素多重結合へのヒドロシアノ化反応とその応用”

有機合成化学協会誌、2019, 77, 341-349.

Arai, S.

“Nickel-catalyzed Hydrocyanation of Allenes and Its Application”

Chem. Pharm. Bull. 2019, 67, 397-403.

Arai, S.; Nakazawa, K.; Yang, X.-F.; Nishida, A.

“Nickel-catalyzed regioselective hydrocyanation of terminal alkynes by assistance of a tosyl group.”

Tetrahedron 2019, 75, 2482-2485.

Shigeru Arai, Koki Matsumoto, Atsushi Nishida.

“Cu-catalyzed regio- and stereoselective sulfonylation of multi-substituted allenes.”

Tetrahedron 2019, 75, 1145-1148.

Shigeru Arai, Masaya Nakajima,AtsushiNishida.

“Total Synthesis of Lundrines and Related Alkaloids”

J. Synth. Org. Chem., Jpn. 2018, 76, 668-677.

Kouki Matsumoto, Shigeru Arai, Atsushi Nishida

“Formal Synthesis of (±)-Quebrachamine through regio- and stereoselective hydrocyanation of arylallene”

Tetrahedron 2018, 74, 2865-2870.

“Olefin-migrative Cleavage of Cyclopropane Rings through the Nickel-catalyzed Hydrocyanationof Allenes and Alkenes.”

Hori, H. Arai, S., Nishida A.

Adv. Syn. Catal. 2017, 359, 1170.

“Transfer of Axial Chirality Through the Nickel-catalyzed Hydrocyanation of Chiral Allenes.”

Amako Y. Arai, S., Nishida A.

Org. Biomol. Chem. 2017, 15, 1612-1617.

“Furan-Iminium Cation Cyclization (FIC) in A Total Synthesisof Manzamine Alkaloids”

Tokumaru,K.; Ohfusa,T.; Arai,S.; Nishida, A.

J. Antibiotics 2016, 69, 340-343.

“Total Syntheses of (+)-Grandilodine C and (+)-Lapidilectine B and Determination of their Absolute Stereochemistry”

Masaya Nakajima, Shigeru Arai and Atsushi Nishida

Angew. Chem. Int. Ed. 2016, 55, 3473-3476.

<highlighted by SYNFACTS 2016, 12, 437.>

“A New Protocol for Nickel-catalysed Regio- and Stereoselective Hydrocyanation of Allenes.”

Shigeru Arai, Hiroto Hori, Yuka Amako, and Atsushi Nishida.

Chem. Commun. 2015, 51, 7493-7496.

“Asymmetric Total Synthesis of (-)-Lundurine B and Determination of Its Absolute Stereochemistry.”

Masaya Nakajima, Shigeru Arai, and Atsushi Nishida.

Chem. Asian J. 2015, 10, 1065-1070.

“A Concise and Versatile Synthesis of Alkaloids from Kopsia tenuis: Total Synthesis of (±)-Lundurine A and B.”

Shigeru Arai, Masaya Nakajima, and Atsushi Nishida.

Angew. Chem. Int. Ed. 2014, 53, 5569-5571.

<highlighted by SYNFACTS 2014, 10, 789.>

“Total Synthesis of (±)-Lundurine B.”

Masaki Hoshi, Osamu Kaneko, Masaya Nakajima, Shigeru Arai, and Atsushi Nishida.

Org. Lett. 2014, 16, 768-771.

<highlighted by SYNFACTS 2014, 10, 338.>

“A 2-Benzothiazolylphenyl Group Accelerates the Intramolecular [2+2] Cycloaddition of Allene-Ynes.”

Hiroto Hori, Shigeru Arai and Atsushi Nishida.

Asian J. Org. Chem. 2014, 3, 41-43.

“Total Synthesis of Schizocommunin and Revision of Its Structure.”

Uehata, Koji; Kimura, Naoki; Hasegawa, Kazuya; Arai, Shigeru; Nishida, Mayumi; Hosoe, Tomoo; Kawai, Ken-ichi; Nishida, Atsushi.

Journal of Natural Products 2013, 76(11), 2034-2039.

“Catalytic Cyanation of Carbon-Carbon Triple Bonds Through a Three-Component Cross-Coupling Reaction under Nickel Catalysis.”

Yang, Xiaofei; Arai, Shigeru; Nishida, Atsushi.

Advanced Synthesis & Catalysis 2013, 355(14-15), 2974-2981.

“Regioselective Hydronickelation of Allenes and Its Application to the Hydrocyanative Carbocyclization Reaction of Allene-Ynes and Bis-Allenes.”

Amako, Yuka; Hori, Hiroto; Arai, Shigeru; Nishida, Atsushi.

Journal of Organic Chemistry 2013, 78(21), 10763-10775

“Hydrocyanative Cyclization and Three-Component Cross-Coupling Reaction between Allenes and Alkynes under Nickel Catalysis.”

Shigeru Arai, Yuka Amako, Xiaofei Yang and Atsushi Nishida.

Angew. Chem. Int. Ed. 2013, 52(31), 8147-8150.

“AntiCarbocyanative Cyclization of Enynes under Nickel Catalysis.”

Tomohiro Igarashi, Shigeru Arai, and Atsushi Nishida.

J. Org. Chem. 2013, 78(9), 4366-4372.

“Palladium-Catalyzed Cyanation of Non-Activated Alkynes; Development of Cyanopalladationand Its Application to Cyclization and Cycloaddition Reactions.”

Arai, S.; Nishida, A.

Synlett 2012, 23, 2880-2893. (invited accounts).

“Catalytic dicyanative 5-exo- and 6-endo-cyclization triggered by cyanopalladation of alkynes.”

Shigeru Arai, Yuka Koike, and Atsushi Nishida.

Adv. Synth. Catal. 2010, 352, 893-900.

“Catalytic Dicyanative [4 + 2] Cycloaddition Triggered by Cyanopalladation Using Ene-Enynes and Cyclic Enynes with Methyl Acrylate.”

Shigeru Arai, Yuka Koike, Hirohiko Hada, and Atsushi Nishida.

J. Org. Chem. 2010, 75, 7573-7579.

“Catalytic Dicyanative [4+2] Cycloaddition Triggered by Cyanopalladation of Conjugated Enynes under Aerobic Conditions.”

Shigeru Arai, Yuka Koike, Hirohiko Hada, and Atsushi Nishida.

J. Am. Chem. Soc. 2010, 132, 4522-4523.

“Palladium-Catalyzed Cyanation of Carbon-Carbon Triple Bonds under Aerobic Conditions.”

Arai, S.; Sato, T.; Koike, Y.; Hayashi, M.; Nishida, A.

Angew. Chem. Int. Ed. 2009, 48, 4528-4531.

<highlighted in Synth. Org. Chem. Jpn. 2010, 68, 567.>

“Asymmetric synthesis of hydroisoquinoline derivatives, a key intermediate for manzamine synthesis, by Diels-Alder reaction using 4-amino-2-siloxybutadiene.”

Mihara, Yasuhiro; Matsumura, Tomoaki; Terauchi, Yuki; Akiba, Masakatsu; Arai, Shigeru; Nishida, Atsushi.

Bulletin of the Chemical Society of Japan 2009, 82(12), 1520-1527.

“Catalytic 1,2-Dicyanation of Alkynes by Palladium(II) under Aerobic Conditions.”

Arai, Shigeru; Sato, Takashi; Nishida, Atsushi.

Advanced Synthesis & Catalysis 2009, 351(11+12), 1897-1904.

“Novel Synthesis of Cinnolines and 1-Aminoindolines via Cu-Catalyzed Intramolecular N-Arylation of Hydrazines and Hydrazones Prepared from 3-Haloaryl-3-hydroxy-2-diazopropanoates.”

Kazuya Hasegawa, Naoki Kimura, Shigeru Arai, and Atsushi Nishida.

J. Org. Chem., 2008, 73(16), 6363-6368.

“Synthetic Study of Manzamine B; Synthesis of the Tricyclic Central Core by an Asymmetric Diels-Alder and RCM Strategy.”

Tomoaki Matsumura, Masakatsu Akiba, Shigeru Arai, Masako Nakagawa and Atsushi Nishida.

Tetrahedron Letters. 2007, 48, 1265-1268.

“Catalytic Asymmetric Michael Reaction under Phase-Transfer Catalysis; Construction of Chiral Tetrasubstituted Carbon and its Application to the Synthesis of a Chiral Pyrrolidone.”

Shigeru Arai, Fumie Takahashi, Riichiro Tsuji, and Atsushi Nishida.

Heterocycles, 2006, 67, 495-501.

“Synthesis of alpha-Diazo-beta-hydroxyesters through a One-Pot Protocol by Phase-Transfer Catalysis: Application to Enantioselective Aldol-Type Reaction and Deastereoselective Synthesis of alpha-Amino-beta-hydroxyester Derivatives.”

Kazuya Hasegawa, Shigeru Arai, and Atsushi Nishida.

Tetrahedron, 2006, 62, 1390-1401."

“Stereoselective Furan-Iminium Cation Cyclization in the Construction of the Core Structure of Manzamine A.”

Kazuyuki Tokumaru, Shigeru Arai and Atsushi Nishida.

Organic Letters, 2006, 8,　27-30.

“Synthesis of a-Diazo-b-hydroxyesters through a One-Pot Protocol by Phase-Transfer Catalysis: Application to Enantioselective Aldol-Type Reaction and Deastereoselective Synthesis of a-Amino-b-hydroxyester Derivatives.”

Kazuya Hasegawa, Shigeru Arai, and Atsushi Nishida.

Tetrahedron, 2006, 62, 1390-1401.

“Catalytic Asymmetric Michael Reaction under Phase-Transfer Catalysis; Construction of Chiral Tetrasubstituted Carbon and its Application to the Synthesis of a Chiral Pyrrolidone.”

Shigeru Arai, Fumie Takahashi, Riichiro Tsuji, and Atsushi Nishida.

Heterocycles, 2006, 67, 495-501.

“Facile and Regioselective Dealkylation of Arylalkylethers Using Niobium(V) Pentachloride.”

Yukinori Sudo, Shigeru Arai, and Atsushi Nishida.

Euro. J. Org. Chem. 2006, 3, 752-758.

“Facile Synthesis of Vicinal Diamines Promoted by Low-valent Niobium: The Preparation of Chiral Octahydrobisisoquinolines and its Application to Catalytic Asymmetric Synthesis.” 

Shigeru Arai, Satoshi Takita, and Atsushi Nishida.

Euro. J. Org. Chem. 2005, 5262-5267.

“Diastereoselective Fischer-Type Pyrroloindole Synthesis and Its Application to the Synthesis of Chiral Pyrroloindole Alkaloids.” Atsushi Nishida, Satoru Ushigome, Ayako Sugimoto, and Shigeru Arai.

Heterocycles, 2005, 66, 181-185.

“Niobium Pentachloride-Silver Perchlorate as an Efficient Catalyst in the Friedel-Crafts Acylation and Sakurai-Hosomi Reaction of Acetals.”

Shigeru Arai, Yukinori Sudo, and Atsushi Nishida.

Tetrahedron, 2005, 61, 4639-4642.

“One-pot Synthesis of α-Diazo-β-hydroxyesters under Phase-Transfer Catalysis and Application to the Catalytic Asymmetric Aldol Reaction.”

Shigeru Arai, Kazuya Hasegawa and Atsushi Nishida.

Tetrahedron Letters, 2004, 45, 1023-1026.

“A Highly Diastereoselective Pinacol Coupling Reaction of Aldehydes and Ketones Using Low-valence Niobium Generated from Nb(V).”

Shigeru Arai, Yukinori Sudo and Atsushi Nishida.

Chem. Pharm. Bull., 2004, 52 (2), 287-288.

“Novel Synthesis of Fused Indoles by the Palladium-Catalyzed Cyclization of N-Cycloalkenyl-o-haloanilines.”

Takeshi Watanabe, Shigeru Arai, Atsushi Nishida.

Synlett, 2004, 907-909.

“A Simple and Regioselective Carbon-Oxygen Bond Cleavage Using Niobim(V).”

Shigeru Arai, Yukinori Sudo and Atsushi Nishida.

Synlett, 2004, 1104-1106.

“General Method for the Synthesis of Chiral 2,3-Bisarylmethoxy-1,4-butanediols from (L)-(+)-Tartarate.”

Riichiro Tsuji, Shigeru Arai, Atsushi Nishida.

Synthesis, 2004, 960-966 (Featured Article).

山次研究室の論文はこちら